Inhibition of protein synthesis in cell-free systems by homocitrullylamino adenosine

Inhibition of protein synthesis in cell-free systems by homocitrully lamino adenosine.

Homocitrullylamino adenosine inhibits the incorporation of Ii4Clamino acids into a hot acid-insoluble form in cell-free systems derived from Escherichia coli and rat liver. The concentration necessary for one-half maximal inhibition in the E. coli system is i.l. Io -4 M. Addition of the intact molecule is necessary for the maximum inhibition. The inhibition does not appear to involve the activa...

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Inhibition of Protein Synthesis in Mammalian Cell-free Systems by Ci-iloramphenicol*, by Austin

Although chloramphenicol is known to inhibit microbial protein synthesis both in intact cells (1-3) and in cell-free systems (4--8), similar inhibition of protein synthesis does not occur in analogous mammalian systems unless large amounts of chloramphenicol are employed (9-12). The difference in sensitivity to chloramphenicol is most striking in cell-free systems, where cellular permeability i...

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Tetracycline Inhibition of Cell-Free Protein Synthesis

DAY, L. E. (Chas. Pfizer & Co., Inc., Groton, Conn.). Tetracycline inhibition of cell-free protein synthesis. II. Effect of the binding of tetracycline to the components of the system. J. Bacteriol. 92:197-203. 1966.-When tetracycline, an inhibitor of cell-free protein synthesis, was preincubated with each component of the Escherichia coli cell-free system, i.e., ribosomes, soluble ribonucleic ...

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Tetracycline Inhibition of Cell-Free Protein Synthesis

DAY, L. E. (Chas. Pfizer & Co., Inc., Groton, Conn.). Tetracycline inhibition of cell-free protein synthesis. II. Effect of the binding of tetracycline to the components of the system. J. Bacteriol. 92:197-203. 1966.-When tetracycline, an inhibitor of cell-free protein synthesis, was preincubated with each component of the Escherichia coli cell-free system, i.e., ribosomes, soluble ribonucleic ...

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Tetracycline Inhibition of Cell-Free Protein Synthesis

DAY, L. E. (Chas. Pfizer & Co., Inc., Groton, Conn.). Tetracycline inhibition of cell-free protein synthesis. II. Effect of the binding of tetracycline to the components of the system. J. Bacteriol. 92:197-203. 1966.-When tetracycline, an inhibitor of cell-free protein synthesis, was preincubated with each component of the Escherichia coli cell-free system, i.e., ribosomes, soluble ribonucleic ...

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Inhibition of protein synthesis in cell-free systems by homocitrullylamino adenosine

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